A Very Rare Case -  Hairy Cell Leukemia in Patient with Sarcoidosis.

نویسندگان

  • N Karadurmus
  • G Erdem
  • Y Basaran
  • I Naharci
  • C Tasci
  • T Dogan
  • A Ifran
  • K Kaptan
  • K Saglam
  • C Beyan
چکیده

Although the coexistence of hairy cell leukemia with sarcoidosis has been reported in a few cases in the literature, in our case the patient had been diagnosed and followed about 10 years with sarcoidosis and massive splenomegaly. It has been demonstrated that T helper 1 cells exist in organs influenced by sarcoidosis. These cells produce IL-2 and IFN-γ and induce a nonspecific inflammatory response and granuloma formation. Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia -  sarcoidosis - massive splenomegaly.

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عنوان ژورنال:
  • Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

دوره 28 3  شماره 

صفحات  -

تاریخ انتشار 2015